4°C, sealed storage, away from moisture
生物活性
Cloprostenol sodium salt (ICI 80996 sodium salt) is a potent synthetic prostaglandin analogue, acts as a luteolytic agent, and is a PGF2α receptor agonist.
性状
Solid
IC50 & Target[1][2]
PGF2α receptor
体外研究(In Vitro)
Cloprostenol is a PGF2α receptor agonist.
Cloprostenol (0.1 μM) counteracts the adipogenic effects of statil, on both intracellular lipid accumulation and expression of transcripts for proadipogenic factors C/EBPα and PPARγ after treatment for 6 days.
Medlife has not independently confirmed the accuracy of these methods. They are for reference only.
体内研究(In Vivo)
Cloprostenol sodium salt (25 μg) decreases plasma progesterone in pregnant rats.
Medlife has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件
Room temperature or refrigerated transportation.
储存方式
4°C, sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
参考文献
[1]. Salazar H, et al. Luteolytic effects of a prostaglandin analogue, cloprostenol (ICI 80,996), in rats: ultrastructural and biochemical observations. Biol Reprod. 1976 May;14(4):458-72. [Information]
[2]. Pastel E, et al. Aldose reductases influence prostaglandin F2α levels and adipocyte differentiation in male mouse and human species. Endocrinology. 2015 May;156(5):1671-84. [Information]
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