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★【medlife】(±)-Cloprostenol sodium salt
2024年06月07日 17:02   化工产品  

关键词:(±)-Cloprostenol sodium salt
中文名称
(±)-Cloprostenol sodium salt
中文别名
氯前列醇钠;氯前列烯醇钠;7-[2-[4-(3-氯苯氧基)-3-羟基丁-1-烯基]-3,5-二***]庚-5-烯酸钠;氯比前列腺素钠;前列烯醇钠;氯前列醇钠(D型);氯前列醇钠(DL型);DL-氯前列醇钠;(±)-氯前列醇钠;DL-氯前列醇钠盐;反式-4-乙基环己烷甲酸;氯前列醇钠 API;氯前列醇钠标准品;氯前列烯醇钠 USP标准品;(+/-)-氯前列醇钠盐水合物
英文名称
(±)-Cloprostenol sodium salt
英文别名
(+)-cloprostenol sodium;15-EPI CLOPROSTENOL;15(S)-CLOPROSTENOL;16-(3-CHLOROPHENOXY)-9,11,15R-TRIHYDROXY-17,18,19,20-TETRANORPROSTA-5Z,13E-DIEN-1-OIC ACID SODIUM SALT;(+)-16-M-CHLOROPHENOXY TETRANOR PROSTAGLANDIN F2ALPHA SODIUM SALT;16-(M-CHLOROPHENOXY)-TETRANOR-PROSTAGLANDIN-F2ALPHA, SODIUM SALT;(+/-)-9ALPHA,11ALPHA,15-TRIHYDROXY-16-(3-CHLOROPHENOXY)-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID, SODIUM SALT;(+/-)-9ALPHA,11ALPHA,15S-TRIHYDROXY-16-(3-CHLOROPHENOXY)-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID;(+)-9ALPHA,11ALPHA,15R-TRIHYDROXY-16-(3-CHLOROPHENOXY)-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID, SODIUM SALT;(5Z)-rel-Cloprostenol Sodium;(+/-)-Cloprostenol sodium salt hydrate;(±)-Cloprostenol sodium;(±)-Cloprostenol sodium salt;Cloprostenol (sodium salt);Cloprostenol Sodium;Cloprostenol sodium salt;Sodium [1alpha(Z),2beta(1E,3R*),3alpha,5alpha]-(+/-)-7-[2-[4-(3-chlorophenoxy)-3-hydroxybut-1-enyl]-3,5-dihydroxycyclopentyl]hept-5-enoate;Estrumate;(+/-)-Cloprostenol sodium salt;81129I41BJ;ICI 80996;Estroplan;C22H28ClNaO6;(+)-CLOPROSTENOL SODIUM SALT;Cloprostenol sodium [USAN:USP];Sodium (Z)-7-((1R,2R,3R,5S)-2-((R,E)-4-(3-chlorophenoxy)-3-hydroxybut-1-en-1-yl)-3,5-dihydroxycyclopentyl)hept-5-enoate;CLOPROSTENOL Na;D-Cloprostenol sodium salt;Cloprostenol sodium, (+)-;DSSTox_RID_81
Cas No.
55028-72-3
分子式
C22H28ClNaO6
分子量
446.90
包装储存

4°C, sealed storage, away from moisture


生物活性
Cloprostenol sodium salt (ICI 80996 sodium salt) is a potent synthetic prostaglandin analogue, acts as a luteolytic agent, and is a PGF2α receptor agonist.
性状
Solid
IC50 & Target[1][2]
PGF2α receptor
体外研究(In Vitro)
Cloprostenol is a PGF2α receptor agonist.
Cloprostenol (0.1 μM) counteracts the adipogenic effects of statil, on both intracellular lipid accumulation and expression of transcripts for proadipogenic factors C/EBPα and PPARγ after treatment for 6 days.
Medlife has not independently confirmed the accuracy of these methods. They are for reference only.
体内研究(In Vivo)
Cloprostenol sodium salt (25 μg) decreases plasma progesterone in pregnant rats.
Medlife has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件
Room temperature or refrigerated transportation.
储存方式
4°C, sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
参考文献
[1]. Salazar H, et al. Luteolytic effects of a prostaglandin analogue, cloprostenol (ICI 80,996), in rats: ultrastructural and biochemical observations. Biol Reprod. 1976 May;14(4):458-72.  [Information]
[2]. Pastel E, et al. Aldose reductases influence prostaglandin F2α levels and adipocyte differentiation in male mouse and human species. Endocrinology. 2015 May;156(5):1671-84.  [Information]


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