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quinine dihydrochloride | 60-93-5
60-93-5

Product name:quinine dihydrochloride

CAS No:60-93-5
MF:C20H24N2O2.2(HCL)
MW:397.34
MDL:MFCD00151247
CID:33766
PubChem ID:91429
Introduction
Quinine dihydrochloride, white powder, odorless, extremely bitter taste; Light gradient; The aqueous solution shows acidic reaction. This product is very soluble in water, soluble in ethanol, slightly soluble in chloroform, and very slightly soluble in diethyl ether. It is a quinoline derivative, which can bind to the DNA of Plasmodium to form a complex, inhibit DNA replication and RNA transcription, and thus inhibit the protein synthesis of Plasmodium< Br>
Names and Identifiers
  • quinine dihydrochloride
  • Quinine Dihydochloride
  • acidquininehydrochloride
  • chinindihydrochlorid
  • QUININE DI HCL
  • Quinine dichloride
  • quininebimuriate
  • QuinineDihydrochlorideInjection
  • (6-Methoxy-4-quinolyl)(5-vinyl-1-azabicyclo[2.2.2]oct-2-yl)methanol dihydrochloride
  • MDL:MFCD00151247
  • InChIKey:NNKXWRRDHYTHFP-HZQSTTLBSA-N
  • Inchi:1S/C20H24N2O2.2ClH/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18;;/h3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3;2*1H/t13-,14-,19-,20+;;/m0../s1
  • SMILES:O[C@H](C1=C2C=C(C=CC2=NC=C1)OC)[C@H]3N4CC[C@@]([H])(C3)[C@@H](C=C)C4.[H]Cl.[H]Cl
Chemical and Physical Properties

Computed Properties

  • Exact Mass: 396.13700
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 4
  • Rotatable Bond Count: 4
  • Heavy Atom Count: 26

Experimental Properties

  • LogP: 4.71510
  • PSA: 45.59000
  • Boiling Point: 495.9°C at 760 mmHg
  • Melting Point: 238-2400C
  • Stability/Shelf Life: Stable, but may be light sensitive. Efflorescent. Incompatible with strong oxidizing agents.
Security Information
  • Safety Term:6.1(b)
  • Safety Instruction:S26; S36
  • Packing Group:III
  • Packing Group:III
  • Risk Phrases:R36/37/38
  • Hazard Level:6.1(b)
  • Znak za nevarno blago: Xi Xi
  • Hazardous Material transportation number:1544
  • Hazard Statement:H302-H315-H319-H335
  • Warning Statement:P261-P305+P351+P338
  • Storage Condition:(BD150062)
  • PackingGroup:III
  • Hazard Category Code:36/37/38
  • Signal Word:Warning
  • HazardClass:6.1(b)
Customs Data
  • HS CODE:2939200000
  • Customs Data:

    China Customs Code:

    2939200000
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