(R)-(+)-美托洛尔 | 81024-43-3
中文名称:
(R)-(+)-美托洛尔
英文名称:
(R)-Metoprolol
CAS No.:
81024-43-3
分子式:
C1 5 H2 5 NO3
分子量:
267.363904714584
名称和标识符
MDL
MFCD00869311
InChIKey
IUBSYMUCCVWXPE-CQSZACIVSA-N
Inchi
1S/C15H25NO3/c1-12(2)16-10-14(17)11-19-15-6-4-13(5-7-15)8-9-18-3/h4-7,12,14,16-17H,8-11H2,1-3H3/t14-/m1/s1
SMILES
O(C1C=CC(CCOC)=CC=1)C[C@H](O)CNC(C)C
别名信息
- 中文别名 -
(R)-(+)-美多心安
(R)-(+)-美托洛尔
美托洛尔
- 英文别名 -
2-Propanol,1-[4-(2-methoxyethyl)phenoxy]-3-[(1-methylethyl)amino]-, (2R)-
(R)-(+)-METOPROLOL
(R)-Metoprolol
(+)-Metoprolol
(2R)-metoprolol
(R)-1-isopropylamino-3-[4-(2-metoxyethyl)phenoxy]propan-2-ol
BIDD:GT0581
d-Metoprolol
(2R)-1-[4-(2-Methoxyethyl)phenoxy]-3-[(1-methylethyl)amino]-2-propanol (ACI)
2-Propanol, 1-[4-(2-methoxyethyl)phenoxy]-3-[(1-methylethyl)amino]-, (R)- (ZCI)
(R)-(+)-Metoprolol
2-Propanol 1-[4-(2-methoxyethyl)phenoxy]-3-[(1-methylethyl)amino]-, (2R)-
物化性质
实验特性
LogP
2.00410
PSA
50.72000
熔点
39-42°C
计算特性
相关文献
1.
Enantiomeric Separation and Sensitive Detection of Propranolol, Metoprolol and Atenolol Derivatized With a Fluorogenic Reagent, 4-(N-Chloroformylmethyl-N- methyl)amino-7-N,N-dimethylaminosulfonyl-2,1,3- benzoxadiazole (DBD-COCl), on Cellulose Chiral Columns in the Reversed-phase Mode
Xiangjing Yang,Takeshi Fukushima,Tomofumi Santa,Hiroshi Homma Analyst 1997 122 1365
2.
Metoprolol: solid forms of a top selling antihypertensive
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3.
Effect of Ling-Gui-Zhu-Gan decoction major components on the plasma protein binding of metoprolol using UPLC analysis coupled with ultrafiltration
Peng Zhou,Jinling Huang,Wanxue Ding RSC Adv. 2018 8 35981
4.
Simultaneous determination of ivabradine, metoprolol and their metabolites in rat plasma by ultra-performance liquid chromatography tandem mass spectrometry and its application in a pharmacokinetic study
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Identifying a selective oligopeptide clamp in the gas phase
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6.
The degradation and persistence of five pharmaceuticals in an artificial climate incubator during a one year period
Lina Yin,Ruixue Ma,Bin Wang,Honglin Yuan,Gang Yu RSC Adv. 2017 7 8280
7.
Photo-induced environmental depletion processes of β-blockers in river waters
Qin-Tao Liu,Rob I. Cumming,Alan D. Sharpe Photochem. Photobiol. Sci. 2009 8 768
8.
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9.
Mesoporous silica-based nanodevices for biological applications
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10.
Kinetic resolution of (RS)-1-chloro-3-(4-(2-methoxyethyl)phenoxy)propan-2-ol: a metoprolol intermediate and its validation through homology model of Pseudomonas fluorescens lipase
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