简介名称和标识符别名信息物化性质安全信息生产方法和用途相关文献专业数据库参考相关分类相关产品

羟基积雪草酸 | 18449-41-7

中文名称：羟基积雪草酸

英文名称： Madecassic acid

CAS No.： 18449-41-7

分子式： C₃₀H₄₈O₆

分子量： 504.6985

如需查看该化合物的详细结构式,mol文件,smile,InChi 请点击：羟基积雪草酸结构式

MSDS：羟基积雪草酸MSDS

PubChem CID： 51531966

价格行情：羟基积雪草酸价格

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羟基积雪草酸的其他展现形式

相关化合物

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简介

Madecassic acid 分离自积雪草(伞形科)。Madecassic acid 具有 iNOS，COX-2，TNF-α，IL-1beta 和 IL-6 抑制作用，可通过在 RAW 264.7 巨噬细胞中下调 NF-κB 激活而具有抗炎作用。

名称和标识符

MDL	MFCD29048539
InChIKey	PRAUVHZJPXOEIF-HTKBEAEASA-N
Inchi	1S/C30H48O6/c1-16-9-10-30(25(35)36)12-11-28(5)18(22(30)17(16)2)7-8-21-26(3)13-20(33)24(34)27(4,15-31)23(26)19(32)14-29(21,28)6/h7,16-17,19-24,31-34H,8-15H2,1-6H3,(H,35,36)/t16?,17?,19?,20?,21-,22+,23-,24?,26-,27+,28-,29-,30+/m1/s1
SMILES	O([H])C1([H])C([H])([H])[C@@]2(C([H])([H])[H])[C@]3(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]4(C(=O)O[H])C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])(C([H])([H])[H])[C@@]4([H])C3=C([H])C([H])([H])[C@]2([H])[C@@]2(C([H])([H])[H])C([H])([H])C([H])(C([H])([C@@](C([H])([H])[H])(C([H])([H])O[H])[C@@]21[H])O[H])O[H]

别名信息

- 中文别名 -

羟基积雪草酸
羟基积雪草苷
羟基积雪草苷酸, 来源于积雪草
羟基积雪草酸标准品
羟基积雪草酸(P)

羟基积雪草酸(SH)
羟基积雪草酸（标准品）
羟基积雪草酸,madasiatic acid
羟基积雪草酸,Madecassic acid,植物提取物,标准品,对照品
羟基积雪草酸对照品
羟基积雪草酸,Madecassic acid
羟基积雪草苷酸
MADECASSIC ACID 羟基积雪草酸
羟基积雪草酸(分析标准品)
羟基积雪草酸(对照品)

- 英文别名 -

madasiatic acid
6BETA-HYDROXYASIATIC ACID
(2alpha,3beta,4alpha,6beta)-2,3,6,23-tetrahydroxy-urs-12-en-28-oic acid
MADECASSIC ACID
Urs-12-en-28-oic acid, 2,3,6,23-tetrahydroxy-, (2.alpha.,3.beta.,4.alpha.,6.beta.)-

(1S,2R,4aS,6aS,6aS,6bR,8R,8aR,9R,10R,11R,12aR,14bR)-8,10,11-trihydroxy -9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,1 1,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid
Hydroxy asiaticoside
MADECASSIC ACID(P)
2α,3β,6β,23-Tetrahydroxyurs-12-en-28-oic acid
Brahmic acid
MADECASSIC ACID(P) PrintBack
Urs-12-en-28-oic acid,2,3,6,23-tetrahydroxy-, (2a,3b,4a,6b)-
6-Hydroxyasiatic acid
Brahmanic acid
Brahmsaeure
madecaic acid
Madecassic?acid
MADESIC ACID
madesica acid
6β-Hydroxyasiatic acid
[ "6β-Hydroxyasiatic acid" ]
Madecasoside
Madecassic acid, froM Centella asiatica
Madecassic acid, 98%, from Centella asiatica (L.) Urb.
(4As,6aR,6aS,6bR,8aR,9R,12aR,14bS)-8,10,11-trihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2
Madecassic acid
trihydroxy-9-(hydroxymethyl)-
(1S,2R,4aS,6aS,6bR,8R,9R,10R,11R,12aR)-8,10,11-trihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylic acid
18449-41-7
MFCD29048539
,7,8,8a,9,10,11,12,12a,12b,13,14b-
1,2,6a,6b,9,12a-hexamethyl-1,2,3,4,4a,5,6,6a,6b
(1S,2R,4aS,6aS,6bR,8R,9R,10R,11R,12aR)-8,10,11-
Q-100219
icosahydropicene-4a-carboxylic acid
SCHEMBL24756829
Madecassicside,(S)
UPCMLD-DP049:001
NCGC00161617-01
CHEMBL19097
UPCMLD-DP049
(2alpha,3beta,6beta)-2,3,6,23-tetrahydroxyurs-12-en-28-oic acid
CHEBI:73058
Urs-12-en-28-oic acid, 2,3,6,23-tetrahydroxy-, (2alpha,3beta,4alpha,6beta)-
Callicos CellAwake Mask madecassol
DTXSID70939838
Urs-12-en-28-oic acid, 2,3,6,23-tetrahydroxy-, (2a,3b,4a,6b)-
s9502
MADECASSIC ACID [WHO-DD]
SR-05000002181-3
6.BETA.-HYDROXYASIATIC ACID
AKOS015896782
2alpha,3beta,6beta,23-TETRAHYDROXY-URS-12-EN-28-OIC ACID
ORISTRACT MDA
(1S,2R,4aS,6aR,6aS,6bR,8R,8aR,9R,10R,11R,12aR,14bS)-8,10,11-trihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylicacid
HY-N0569
MADECASSIC ACID [INCI]
BDBM50244879
CCG-208587
(1S,2R,4aS,6aR,6aS,6bR,8R,8aR,9R,10R,11R,12aR,14bS)-8,10,11-trihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid
MADECASSIC ACID (CONSTITUENT OF CENTELLA ASIATICA)
6beta-hydroxyasiatic acid
NSC 88135
2alpha,3beta,6beta,23-Tetrahydroxyurs-12-en-28-oic Acid
NSC-88135
UNII-M7O1N24J82
(1S,2R,4aS,6aS,6bR,8R,8aR,9R,10R,11R,12aR,12bR,14bS)-8,10,11-trihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylic acid
2.ALPHA.,3.BETA.,6.BETA.,23-TETRAHYDROXY-URS-12-EN-28-OIC ACID
SCHEMBL153239
SR-05000002181
AC-6055
NS00071060
URS-12-EN-28-OIC ACID, 2.ALPHA.,3.BETA.,6.BETA.,23-TETRAHYDROXY-
M7O1N24J82
CHEMBL481854
SR-05000002181-2
MADECASSIC ACID (CONSTITUENT OF CENTELLA ASIATICA) [DSC]
DB14037
URS-12-EN-28-OIC ACID, 2alpha,3beta,6beta,23-TETRAHYDROXY-
CS-0009106
A880771
Madecassic-acid
6?-Hydroxyasiatic acid
ConMedNP.2449
brahmic acid
Madecassic Acid
2,3,6,23-Tetrahydroxy-12-ursen-28-oic acid
(2&#945
,3&#946
,6&#946
)-form

物化性质

实验特性

LogP	4.00350
PSA	118.22000
折射率	1.59
沸点	641.7°C at 760 mmHg
熔点	270°C (dec.)
闪点	355.9±28.0 °C
颜色与性状	Powder
密度	1.2300

计算特性

精确分子量	504.34500
氢键供体数量	5
氢键受体数量	6
可旋转化学键数量	2
同位素质量	504.34508925 g/mol
重原子数量	36
复杂度	963
同位素原子数量	0
确定原子立构中心数量	0
不确定原子立构中心数量	13
确定化学键立构中心数量	0
不确定化学键立构中心数量	0
共价键单元数量	1
疏水参数计算参考值（XlogP）	4.4
拓扑分子极性表面积	118
分子量	504.7

安全信息

安全说明	24/25
危险品标志	Xi
危害声明	H302-H315-H319-H335
警示性声明	P261-P305+P351+P338
储存条件	2-8°C储存
信号词	Warning

生产方法和用途

用途	具有抗炎、抗刺激性、治冠心病、心肌梗死、脑血栓，脑梗塞，增强记忆，皮肤修复、刺激皮肤细胞、祛斑、皮肤增白等。

羟基积雪草酸 | 18449-41-7

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